June 1, 1975Circulation
Technetium stannous pyrophosphate myocardial scintigrams in patients with chest pain of varying etiology.
Key result
Technetium-99m stannous pyrophosphate myocardial imaging accurately detected acute myocardial infarction, with positive scintigrams in 95.0% of AMI patients and 8.9% of non-AMI patients.
Why the study?
Does Technetium-99m stannous pyrophosphate myocardial imaging accurately detect acute myocardial infarction in patients with chest pain of uncertain etiology?
Population
202 patients admitted to the hospital with chest pain of uncertain etiology
Comparison
Technetium-99m stannous pyrophosphate myocardial… vs Clinical, electrocardiographic, and enzymatic…
Design
Cohort
Authors
Discussion
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Implication
May aid AMI detection in uncertain chest pain; leaves open prospective validation against modern biomarkers.
Study Design
Type
Observational (n=202)
Structured PICO
Does Technetium-99m stannous pyrophosphate myocardial imaging accurately detect acute myocardial infarction in patients with chest pain of uncertain etiology?
P
Population
202 patients admitted to the hospital with chest pain of uncertain etiology
I
Intervention
Technetium-99m stannous pyrophosphate myocardial imaging
C
Comparator
Clinical, electrocardiographic (ECG), and enzymatic evidence of acute myocardial infarction
O
Outcome
Correlation of myocardial scintigrams with ECG and enzymatic identification of infarctionsurrogate
Main Result
Absolute Event Rate: 95% vs 8.9%
Technetium-99m stannous pyrophosphate myocardial imaging correlates well with ECG and enzymatic evidence for detecting acute myocardial infarction in patients with chest pain.
Cite This Study
Willerson et al. (1975) conducted an observational in Chest pain of uncertain etiology (n=202). Technetium-99m stannous pyrophosphate myocardial imaging vs. Clinical, ECG, and enzymatic evidence was evaluated on Positive myocardial scintigrams. Technetium-99m stannous pyrophosphate myocardial imaging accurately detected acute myocardial infarction, with positive scintigrams in 95.0% of AMI patients and 8.9% of non-AMI patients.