Acute subendocardial myocardial infarction in patients. Its detection by Technetium 99-m stannous pyrophosphate myocardial scintigrams.
Key result
Technetium-99m stannous pyrophosphate myocardial scintigrams correctly identified acute subendocardial myocardial infarction in 100% of cases (17/17) and were negative in all 71 patients without it.
Why the study?
Does technetium-99m stannous pyrophosphate myocardial scintigraphy accurately detect acute subendocardial myocardial infarction in patients with chest pain?
Population
88 patients admitted to a coronary care unit with chest pain of varying etiology but without ECG evidence of…
Design
Cohort
Authors
Discussion
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Implication
May aid subendocardial MI detection without ECG changes; hypothesis-generating and requires prospective validation before practice change.
Study Design
Type
Observational (n=88)
Structured PICO
Does technetium-99m stannous pyrophosphate myocardial scintigraphy accurately detect acute subendocardial myocardial infarction in patients with chest pain?
P
Population
88 patients admitted to a coronary care unit with chest pain of varying etiology but without ECG evidence of an acute transmural myocardial infarction
I
Intervention
Technetium-99m stannous pyrophosphate (99m-Tc-PYP) myocardial scintigrams
O
Outcome
Detection of acute subendocardial myocardial infarction (correlation of positive scintigram with ECG and enzymatic evidence)surrogate
Main Result
Absolute Event Rate: 100% vs 0%
Technetium-99m stannous pyrophosphate myocardial scintigraphy can accurately identify the presence of acute subendocardial myocardial infarction in patients presenting with chest pain without transmural ECG changes.
Limitations
- The absolute frequency with which subendocardial myocardial infarction can be recognized utilizing this technique will have to be established in a larger number of patients.
- The absolute frequency with which subendocardial myocardial infarction can be recognized utilizing this technique will have to be established in a larger number of patients in the future.
Cite This Study
Willerson et al. (1975) conducted an observational in Chest pain without ECG evidence of acute transmural myocardial infarction (n=88). Technetium-99m stannous pyrophosphate (99m-Tc-PYP) myocardial scintigrams vs. ECG and enzymatic evidence was evaluated on Detection of acute subendocardial myocardial infarction (positive scintigram). Technetium-99m stannous pyrophosphate myocardial scintigrams correctly identified acute subendocardial myocardial infarction in 100% of cases (17/17) and were negative in all 71 patients without it.