Why the study?
Heart failure causes high morbidity, mortality, and reduced quality of life, and this report evaluates the therapeutic benefit of cardiac contractility modulation in an elderly patient with advanced HFrEF despite guideline-directed medical therapy.
Does cardiac contractility modulation (CCM) improve clinical outcomes and quality of life in an elderly patient with advanced HFrEF despite optimal guideline-directed medical therapy?
Does cardiac contractility modulation (CCM) improve clinical outcomes and quality of life in an elderly patient with advanced HFrEF despite optimal guideline-directed medical therapy?
Cardiac contractility modulation (CCM) may offer therapeutic benefits, including improved quality of life and reduced hospitalizations, for patients with advanced HFrEF who remain symptomatic on optimal medical therapy.
Supports CCM in selected HFrEF; extends device options for contractility enhancement in reduced-EF guidelines.
Heart Failure (HF) is a complicated, fatal medical condition that poses a severe threat to human life. It is a complex ailment that can lead to death and is associated with high healthcare costs, significant morbidity and mortality rates, and a reduction in functional capacity and quality of life. Recent data analysis reveals that approximately 64million people worldwide are affected by HF.1 Patients with HFrEF can benefit from cardiac contractility modulation (CCM), a revolutionary device-based treatment. In patients with HFrEF, CCM treatment has been associated with an improvement in exercise tolerance, an improvement in quality of life, a decrease in HF hospitalizations, and a reversal remodeling of the left ventricle. In this instance, we describe the therapeutic benefit of CCM in an elderly individual with advanced HFrEF triggered by ischemic dilated cardiomyopathy who frequently required hospitalization for heart failure-related issues and had a low quality of life despite receiving the best possible guideline-directed medical therapy (GDMT).
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Mohapatra et al. (2023) studied this question.
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