Why the study?
Can a combined MR protocol with phase-contrast technique and MR angiography assess graft flow and patency in patients undergoing CABG surgery?
Can a combined MR protocol with phase-contrast technique and MR angiography assess graft flow and patency in patients undergoing CABG surgery?
A combined MR protocol using phase-contrast and MR angiography effectively assesses bypass patency and flow perioperatively in CABG patients.
Post-CABG LIMA flow decline with native right IMA compensation may reflect adaptation; leaves open whether MR flow assessment alters management.
The objective of this study was to evaluate graft flow (f) and patency (p) in patients with internal mammary artery (f,p) and venous (p only) grafts using a combined MR protocol with phase-contrast technique and MR angiography. 42 patients with 42 left internal mammary artery (LIMA) and 63 venous grafts were examined pre and 6 months post coronary artery bypass graft (CABG) surgery. Phase-contrast flow measurements were applied to the IMA. Post-operatively, a contrast enhanced MR angiogram was performed to assess bypass patency. LIMA/venous grafts were occluded in 3/42 and 13/63, respectively. Flow in LIMA decreased from 19.4+/-10.4 ml min(-1) m(-2) pre-operatively to 13.4+/-9.7 ml min(-1) m(-2) post-operatively (p<0.002). In contrast, flow in the native right IMA increased from 17.6+/-8.7 ml min(-1) m(-2) pre-operatively to 24.8+/-9.0 ml min(-1) m(-2) post-operatively (p<0.001). MRI allows a combined assessment of bypass patency and flow. This study protocol may be applicable to perioperative follow-up studies in patients after CABG surgery.
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Stauder et al. (2005) studied this question.
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