Prognostic Value of Adiponectin for Cardiovascular Disease and Mortality
Why the study?
Do adiponectin levels predict all-cause and CVD mortality and CVD morbidity in adults aged 50-75 years?
Population
2,484 participants, aged 50-75 years, from a population-based cohort in Hoorn, The Netherlands.
Design
Cohort
Authors
Discussion
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Member takes
Implication
Higher adiponectin levels were associated with increased CVD mortality; leaves open whether this reflects compensatory upregulation or a causal marker in older adults.
Structured PICO
Do adiponectin levels predict all-cause and CVD mortality and CVD morbidity in adults aged 50-75 years?
P
Population
2,484 participants, aged 50-75 years, from a population-based cohort in Hoorn, The Netherlands.
I
Intervention
Adiponectin levels (exposure)
O
Outcome
All-cause mortality, cardiovascular disease (CVD) mortality, and CVD morbidityhard clinical
High levels of adiponectin predict mortality, particularly in patients with prevalent cardiovascular disease, suggesting a compensatory upregulation in afflicted individuals.
Cite This Study
Dekker et al. (2008) studied this question.