Why the study?
Is the LPL S447X allele depleted in patients with combined hyperlipidemia compared to controls?
Is the LPL S447X allele depleted in patients with combined hyperlipidemia compared to controls?
The LPL S447X allele is significantly depleted in combined hyperlipidemia cases, suggesting it acts as a protective genetic factor associated with a more favorable lipid profile.
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Suggests protective LPL variant in combined hyperlipidemia; hypothesis-generating and should not yet change practice.
Wung et al. (2006) studied this question.
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