Why the study?
Are LPL HindIII and S447X polymorphisms associated with myocardial infarction and lipid levels in elderly individuals?
Population
343 individuals aged 66-97 years from a Brazilian elderly longitudinal study cohort
Comparison
LPL HindIII and S447X polymorphisms vs Alternative alleles/genotypes of the LPL gene
Design
Cohort
Authors
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Should not yet change practice in elderly patients; leaves open replication and prospective validation of LPL variants.
Are LPL HindIII and S447X polymorphisms associated with myocardial infarction and lipid levels in elderly individuals?
LPL HindIII and S447X polymorphisms are associated with myocardial infarction and altered lipid profiles in an elderly Brazilian population, highlighting their potential role as genetic risk factors.
Gigek et al. (2007) studied this question.
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