Population
Rat plasma and urine, and isolated low-molecular-weight kininogen from rat plasma
Design
Preclinical
Authors
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Arg(1)-kallidin mediates rat tissue kinin effects; extends kallikrein-kinin characterization but leaves open human translation.
The study demonstrates that in rats, the tissue kallikrein-kinin system mediates its effects via Arg(1)-kallidin, structurally analogous to kallidin in other mammals.
Hilgenfeldt et al. (2005) studied this question.
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