Population
In vitro transcription complexes using HeLa whole-cell extract and EA cells
Comparison
Elevated KCl concentrations and addition of… vs Standard KCl concentration and extracts from…
Design
Preclinical
Authors
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Should not yet change practice; leaves open whether transcription factor inactivation drives viral attenuation in vivo.
The block to transcription elongation at the MVM attenuation site late in infection may result from the inactivation of general transcription elongation factors.
Krauskopf et al. (1991) studied this question.
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