Why the study?
Does chronic regional denervation of the ischaemic myocardium reduce reperfusion arrhythmias in a pig model of ischemia?
Population
38 barbiturate anaesthetised open chest pigs in a model with sparse coronary collateral circulation
Comparison
Chronic denervation of the left anteroseptal… vs Sham operated (non-denervated) controls
Design
Preclinical
Follow-up
2 weeks
Authors
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Chronic denervation does not reduce reperfusion VF in pigs; leaves open translation to other models or species.
Does chronic regional denervation of the ischaemic myocardium reduce reperfusion arrhythmias in a pig model of ischemia?
Selective chronic denervation of the ischaemic myocardium does not protect against malignant reperfusion arrhythmias in a pig model.
Cinca et al. (1992) studied this question.
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