Population
Hippocampal pyramidal neurons cultured from 5- to 7-day-old rats
Design
Preclinical
Authors
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Supports KCNQ subunit mapping in rodent neurons; leaves open translation to human physiology or disease.
KCNQ2, KCNQ3, and KCNQ5 subunits contribute to the M-current in cultured rat hippocampal neurons, with variations in TEA sensitivity likely reflecting differential subunit expression.
Shah et al. (2002) studied this question.
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