Population
Transfected Chinese hamster ovary (CHO) cells expressing KCNQ2/KCNQ3 channels
Comparison
Expression of homomeric KCNQ2, homomeric KCNQ3… vs Comparison between homomeric and heteromeric…
Design
Preclinical
Authors
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Homomeric KCNQ properties may not mirror native M-currents; leaves open precise subunit roles in neuronal excitability.
KCNQ2 and KCNQ3 subunits play distinct roles in the expression of M-type potassium currents, with KCNQ2 ensuring surface expression and KCNQ3 modifying channel function.
Selyanko et al. (2001) studied this question.
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