Population
Chinese hamster ovary cells and dissociated rat superior cervical ganglion neurons from postnatal day 17 and…
Comparison
Coexpression of KCNQ2 and KCNQ3 cDNA plasmids… vs Tandem KCNQ3/2 construct
Design
Preclinical
Authors
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Rat data on KCNQ2/3 stoichiometry leave human translation open; extends tandem constructs to native developmental M-currents.
Coexpressed KCNQ2 and KCNQ3 cDNAs generate channels with a 1:1 stoichiometry, and native M channels in SCG neurons adopt this conformation during development.
Hadley et al. (2003) studied this question.
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