Why the study?
Does local anesthesia with mepivacaine and epinephrine prevent hypertension following application of the Mayfield skull-pin head holder in anesthetized neurosurgical patients?
Does local anesthesia with mepivacaine and epinephrine prevent hypertension following application of the Mayfield skull-pin head holder in anesthetized neurosurgical patients?
Infiltration of local anesthetic with epinephrine safely prevents potentially dangerous increases in arterial pressure and heart rate when the Mayfield skull-pin holder is applied during neurosurgery.
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Mepivacaine infiltration prevents hemodynamic surges during skull-pin application; confirms efficacy of local anesthesia in neurosurgical anesthesia.
Levin et al. (1989) studied this question.
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