Why the study?
Does the pentavalent human-bovine reassortant rotavirus vaccine (HBRV) prevent rotavirus gastroenteritis in infants?
Population
Infants
Comparison
Pentavalent human-bovine reassortant rotavirus… vs Placebo
Design
Review
Follow-up
first rotavirus infection season after vaccination
Authors
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May support infant rotavirus vaccination; leaves open long-term durability and real-world effectiveness.
Does the pentavalent human-bovine reassortant rotavirus vaccine (HBRV) prevent rotavirus gastroenteritis in infants?
The pentavalent human-bovine reassortant rotavirus vaccine is highly efficacious and well-tolerated in preventing severe rotavirus gastroenteritis in infants.
Heaton et al. (2005) studied this question.
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