Why the study?
Does a highly stimulated renin response to ACE inhibition correlate with renal hyperfiltration and organ damage in young hypertensive patients?
Population
17 young, previously untreated hypertensive patients with secondary forms of hypertension excluded.
Comparison
ACE inhibition with captopril (captopril test) vs Comparison between patients with highly…
Design
Cohort
Authors
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Highly stimulated post-captopril renin may flag early hyperfiltration and organ damage in young hypertensives; leaves open predictive value and therapeutic targeting.
Does a highly stimulated renin response to ACE inhibition correlate with renal hyperfiltration and organ damage in young hypertensive patients?
A highly stimulated renin response to ACE inhibition in young hypertensive patients may serve as an indicator of early renal hyperfiltration and visceral organ damage.
Erley et al. (1992) studied this question.
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