Why the study?
Does distending the atrial appendages increase heart rate in anaesthetized dogs?
Does distending the atrial appendages increase heart rate in anaesthetized dogs?
Stretching the atrial appendages in dogs triggers a reflex tachycardia mediated by vagal afferent and sympathetic efferent pathways.
Does not support clinical translation; leaves open whether atrial appendage stretch modulates heart rate in humans.
Stretching the atrial appendages in anaesthetized dogs caused an increase in heart rate. This response was unrelated to changes in arterial blood pressure and left and right atrial pressures.2. The increase in heart rate was a reflex response; the afferent path was in the vagi and the efferent solely in the sympathetic nerves.3. The receptors involved in this reflex have been localized to the atrial appendages but there is no conclusive evidence as to their nature.
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Kappagoda et al. (1972) studied this question.
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