Why the study?
Does desflurane improve recovery of consciousness and orientation compared to propofol in healthy female patients undergoing gynaecological laparoscopic surgery?
Does desflurane improve recovery of consciousness and orientation compared to propofol in healthy female patients undergoing gynaecological laparoscopic surgery?
Desflurane provides more rapid recovery of consciousness and orientation compared to propofol after minor gynaecological laparoscopic surgery.
May support faster emergence with desflurane in this setting; hypothesis-generating and requires larger trials before practice change.
Fifty-seven healthy female patients who underwent gynaecological laparoscopic surgery received either desflurane or propofol for induction and maintenance of anaesthesia. Inhalational induction was generally well tolerated, and consciousness was lost in approximately 2 min (mean end-tidal concentrations of desflurane were 8.3% with 60% nitrous oxide, and 7.1% with oxygen). Recovery of consciousness and orientation were more rapid in patients in whom anaesthesia was maintained with desflurane than with propofol, but there were no differences in psychomotor function test scores at 30 min. The data suggest that desflurane provides controllable anaesthesia and rapid recovery of consciousness after laparoscopic surgery.
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Graham et al. (1993) studied this question.
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