What question did this study set out to answer?

The study aims to compare the induction, hemodynamic, and recovery characteristics of desflurane and propofol anesthesia.

May 1, 1993Anesthesia & Analgesia

Desflurane Versus Propofol Anesthesia

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Why the study?

Does desflurane improve induction and recovery characteristics compared to propofol in outpatients undergoing orthopedic surgery?

Population

60 outpatients presenting for orthopedic surgery

Comparison

Desflurane for induction and/or maintenance of… vs Propofol induction followed by propofol infusion…

Design

Other

Follow-up

immediate postoperative period

Authors

MLMiriam Lebenbom-MansourFundación Juan March SPSujit K. PanditUniversity of Michigan SKSarla P. KotharyJaipuria Institute of Management

Discussion

Member takes

Implication

Desflurane maintenance may accelerate emergence in ambulatory outpatients; leaves open optimal induction strategies and needs larger confirmatory trials.

Key Points

The study aims to compare the induction, hemodynamic, and recovery characteristics of desflurane and propofol anesthesia.
Sixty outpatients received one of four different anesthesia protocols for orthopedic surgery.
Patients were divided into four groups based on induction and maintenance anesthetics.
Recovery metrics were assessed, including emergence time and psychomotor function tests.
Group 4 patients emerged from anesthesia significantly faster than Groups 1, 2, and 3, with times of 5.6 +/- 2.0 min vs 10.3 +/- 3.3 min, 8.6 +/- 3.1 min, and 9.3 +/- 1.5 min, respectively.
Group 3 had a higher vomiting rate (50%) compared to Group 2 (0%) and Group 4 (12.5%).
Intermediate recovery was numerically faster in Groups 2 and 4 but not statistically different from Groups 1 and 3.

Structured PICO

Does desflurane improve induction and recovery characteristics compared to propofol in outpatients undergoing orthopedic surgery?

Population

60 outpatients presenting for orthopedic surgery

Intervention

Desflurane (with or without nitrous oxide) for induction and/or maintenance of anesthesia, or propofol induction followed by desflurane and nitrous oxide

Comparator

Propofol induction followed by propofol infusion and nitrous oxide

Outcome

Induction, hemodynamic, and recovery characteristics

Desflurane is a suitable maintenance anesthetic for ambulatory surgery, providing rapid awakening similar to propofol, though it is difficult to use for induction.

Cite This Study

Lebenbom-Mansour et al. (1993) studied this question.

synapsesocial.com/papers/6a719aea8031ec7bb1dd0b22 https://doi.org/10.1213/00000539-199305000-00004

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Implication

Desflurane maintenance may accelerate emergence in ambulatory outpatients; leaves open optimal induction strategies and needs larger confirmatory trials.

Desflurane Versus Propofol Anesthesia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Desflurane Versus Propofol Anesthesia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider