What question did this study set out to answer?

To evaluate recovery and psychomotor performance after desflurane versus isoflurane anesthesia.

September 1, 1991Anesthesia & Analgesia

Psychomotor Performance After Desflurane Anesthesia

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Why the study?

Does desflurane anesthesia improve recovery time and psychomotor performance compared to isoflurane in adult patients undergoing outpatient surgery?

Population

80 ASA physical status I-III adult patients undergoing outpatient surgery. Patients were excluded if they…

Comparison

Desflurane anesthesia vs Isoflurane anesthesia

Design

Other

Follow-up

30 min after discontinuing anesthesia

Authors

JFJames E. FletcherUniversity of North Carolina at Chapel Hill PSPeter S. SebelUniversity of Iowa MMMichael R. MurphyNational Institutes of Health

Discussion

Member takes

Implication

Desflurane may hasten early recovery after outpatient surgery; leaves open whether this improves discharge readiness or sustained psychomotor function.

Key Points

To evaluate recovery and psychomotor performance after desflurane versus isoflurane anesthesia.
80 patients undergoing outpatient surgery were randomly assigned to one of four anesthesia groups.
Psychomotor performance was assessed using choice reaction time and critical flicker fusion threshold.
Patients were excluded if they required postoperative opioids or antiemetics.
Desflurane led to faster awakening (9.45 min for Th-DES-N2O/O2 vs. 13.8 min for Th-ISO-N2O/O2, P<0.05).
Less impairment in choice reaction time in the Th-DES-N2O/O2 group compared to Th-ISO-N2O/O2 group.
At 30 min after anesthesia, more patients in the isoflurane group were too sleepy to perform tests.

Structured PICO

Does desflurane anesthesia improve recovery time and psychomotor performance compared to isoflurane in adult patients undergoing outpatient surgery?

Population

80 ASA physical status I-III adult patients undergoing outpatient surgery. Patients were excluded if they required opioids or antiemetics postoperatively.

Intervention

Desflurane anesthesia (regimens included thiopental induction followed by desflurane in nitrous oxide and oxygen, thiopental induction followed by desflurane in oxygen, or desflurane inhaled induction followed by desflurane in oxygen)

Comparator

Isoflurane anesthesia (thiopental induction followed by isoflurane in nitrous oxide and oxygen)

Outcome

Recovery (time to eye opening) and psychomotor performance (choice reaction time and critical flicker fusion threshold) at 30 min after discontinuing anesthesiasurrogate

Desflurane anesthesia is associated with more rapid initial awakening and less impairment of choice reaction time compared to isoflurane in outpatient surgery.

Cite This Study

Fletcher et al. (1991) studied this question.

synapsesocial.com/papers/6a706b7935aa2c282ce1bce7 https://doi.org/10.1213/00000539-199109000-00005

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Implication

Desflurane may hasten early recovery after outpatient surgery; leaves open whether this improves discharge readiness or sustained psychomotor function.

Psychomotor Performance After Desflurane Anesthesia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Psychomotor Performance After Desflurane Anesthesia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider