Why the study?
Does in situ generation of Angiotensin II play a more important role in forearm vasoconstriction than circulating Angiotensin II in normotensive men?
Population
14 normotensive male volunteers, age 18 to 67 years
Design
Other
Authors
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Local Ang II generation may predominate in forearm vasoconstriction; supports tissue RAS focus but leaves open systemic relevance.
Does in situ generation of Angiotensin II play a more important role in forearm vasoconstriction than circulating Angiotensin II in normotensive men?
In situ generation of Angiotensin II via ACE is more important for local vasoconstriction than circulating Angiotensin II.
Saris et al. (2000) studied this question.
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