December 1, 1991Pacing and Clinical Electrophysiology
Benefits of Smaller Electrode Surface Area (4 mm2) on Steroid‐Eluting Leads
Why the study?
Does a 4 mm2 electrode surface area on steroid-eluting leads improve pacing impedance and threshold compared to an 8 mm2 lead in patients requiring pacemakers?
Population
22 patients requiring pacemaker implantation
Comparison
Pacemaker lead with 4 mm2 electrode surface area… vs Standard-sized 8 mm2 lead with 1 mg dexamethasone
Design
Cohort
Follow-up
12 weeks
Authors
Discussion
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Implication
May reduce energy needs with 4 mm² leads; hypothesis-generating for smaller generators, pending randomized data.
Structured PICO
Does a 4 mm2 electrode surface area on steroid-eluting leads improve pacing impedance and threshold compared to an 8 mm2 lead in patients requiring pacemakers?
P
Population
22 patients requiring pacemaker implantation
I
Intervention
Pacemaker lead with 4 mm2 electrode surface area and 0.5 mg dexamethasone
C
Comparator
Standard-sized 8 mm2 lead with 1 mg dexamethasone
O
Outcome
Pacing threshold, impedance, and sensing threshold at implantation and after 1, 4, and 12 weekssurrogate
A smaller 4 mm2 steroid-eluting pacemaker lead provides higher pacing impedance without compromising pacing threshold, reducing energy requirements and potentially allowing for smaller pulse generators.
Cite This Study
Schuchert et al. (1991) studied this question.