Why the study?
Does exercise training improve endothelium-dependent vasorelaxation in male New Zealand White rabbits?
Population
Male New Zealand White rabbits
Comparison
Exercise training on a treadmill vs Control group (no exercise training)
Design
Preclinical
Follow-up
8 weeks
Authors
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Supports exercise effects on endothelial relaxation in rabbits; leaves open translation to human vascular disease.
Does exercise training improve endothelium-dependent vasorelaxation in male New Zealand White rabbits?
Exercise training enhances endothelium-dependent vasodilation to acetylcholine in the thoracic aorta and pulmonary artery of rabbits, likely via stimulated EDRF release rather than altered smooth muscle response.
Chen et al. (1993) studied this question.
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