Why the study?
Does chronic exercise improve endothelial calcium signaling and vasodilatation in hypercholesterolemic rabbits?
Population
Male New Zealand White rabbits fed rabbit chow with or without 2% cholesterol
Comparison
Chronic exercise vs Control group (no exercise)
Design
Preclinical
Follow-up
8 weeks
Authors
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Hypothesis-generating in hypercholesterolemic rabbits; human trials needed before clinical translation.
Does chronic exercise improve endothelial calcium signaling and vasodilatation in hypercholesterolemic rabbits?
Chronic exercise partially reverses the impairment of endothelial calcium signaling and vasodilatation induced by hypercholesterolemia in a rabbit model.
Jen et al. (2002) studied this question.
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