Population
Four-week-old male Wistar rats
Comparison
Chronic exercise vs Control group (presumably sedentary)
Design
Preclinical
Follow-up
10 weeks
Authors
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Hypothesis-generating for exercise effects on endothelial calcium signaling; human studies required before any clinical translation.
Chronic exercise enhances endothelium-dependent vasodilating responses by increasing ACh-induced intracellular calcium elevation via facilitated calcium influx.
Chu et al. (2000) studied this question.
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