Key result
Older adults and those with diabetes showed limited blood flow reserve to heat stress, with non-significant increases of 5% and 6% from 24°C to 32°C environments (P=0.12 and P=0.14).
Why the study?
Does aging and diabetes impair the vascular endothelial blood flow response to combined local and global heat stress?
Population
Older subjects, younger subjects, and subjects with diabetes.
Comparison
Exposure to three global temperatures combined… vs Comparison between younger, older, and diabetic…
Design
Cross-sectional
Authors
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Impaired microvascular heat response in older adults and diabetes is hypothesis-generating; leaves open endothelial mechanisms and clinical heat risk pending prospective data.
Cross-Sectional
Does aging and diabetes impair the vascular endothelial blood flow response to combined local and global heat stress?
Older individuals and those with diabetes have reduced vascular endothelial blood flow reserve in response to combined local and global heat stress compared to younger individuals.
McLellan et al. (2009) conducted a cross-sectional in Aging and Diabetes. Global and local heat stress vs. Younger subjects was evaluated on Blood flow response of the skin of the foot. Older adults and those with diabetes showed limited blood flow reserve to heat stress, with non-significant increases of 5% and 6% from 24°C to 32°C environments (P=0.12 and P=0.14).
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