Key result
Bare metal stenting followed by paclitaxel-coated balloon dilation was noninferior to paclitaxel-eluting stents for in-stent late lumen loss (0.21 vs 0.30 mm; P<0.05 for noninferiority).
Why the study?
Does a bare metal stent followed by paclitaxel coated balloon dilation reduce in-stent late lumen loss compared to a paclitaxel eluting stent in patients undergoing PCI for de novo coronary lesions?
RCT (n=202)
randomized
Yes
Does a bare metal stent followed by paclitaxel coated balloon dilation reduce in-stent late lumen loss compared to a paclitaxel eluting stent in patients undergoing PCI for de novo coronary lesions?
Absolute Event Rate: 0.21% vs 0.3%
p-value: p=< 0.05 for noninferiority
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Paclitaxel delivery via drug-coated balloon after bare metal stenting achieved comparable angiographic results to paclitaxel-eluting stents but was associated with a higher rate of early stent thrombosis.
Żurakowski et al. (2015) conducted an RCT in de novo coronary lesions (n=202). Bare metal stent followed by paclitaxel coated balloon dilation vs. Paclitaxel eluting stent was evaluated on in-stent late lumen loss (p=< 0.05 for noninferiority). Bare metal stenting followed by paclitaxel-coated balloon dilation was noninferior to paclitaxel-eluting stents for in-stent late lumen loss (0.21 vs 0.30 mm; P<0.05 for noninferiority).
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