Key result
Volume expansion of lactated Ringer's solution was significantly greater during induction of general anesthesia compared to epidural anesthesia in elderly patients (P<0.05 or 0.01).
Why the study?
Does lactated Ringer's solution have different volume expansion efficacy during induction of general versus epidural anesthesia in elderly patients?
Does lactated Ringer's solution have different volume expansion efficacy during induction of general versus epidural anesthesia in elderly patients?
Volume expansion of lactated Ringer's solution is greater during induction of general anesthesia compared to epidural anesthesia in elderly patients.
Anesthesia type may influence lactated Ringer's dosing in elderly patients; leaves open randomized confirmation before practice change.
Objective To compare the volume kinetics of lactated Ringer' s solution during induction of general and epidural anesthesia in elderly patients.Methods Forty ASA Ⅰ or Ⅱ patients,aged 66-86 yr,weighing 45-86 kg,undergoing elective surgery,were studied.In epidural anesthesia group (n =20),lactated Ringer' s solution was infused intravenously starting from 10 min before epidural anesthesia was performed with local anesthetics.In general anesthesia group (n =20),lactated Ringer' s solution 1000 ml was infused intravenously over 60 min starting from 20 min before induction of anesthesia.Arterial blood samples were obtained every 5 min for measurement of hemoglobin concentrations.The plasma dilution,volume increase,and volume expansion efficacy were calculated.Results The plasma dilution,volume increase and volume expansion were significantly higher at 30-60 min of lactated Ringer' s solution infusion in general anesthesia group than in epidural anesthesia group (P ＜ 0.05 or 0.01).Conclusion The volume expansion of lactated Ringer' s solution is greater in elderly patients during induction of general anesthesia than that during induction of epidural anesthesia.
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Xu et al. (2013) studied Elective surgery (n=40). Lactated Ringer's solution during general anesthesia vs. Lactated Ringer's solution during epidural anesthesia was evaluated on Plasma dilution, volume increase, and volume expansion (p=<0.05 or 0.01). Volume expansion of lactated Ringer's solution was significantly greater during induction of general anesthesia compared to epidural anesthesia in elderly patients (P<0.05 or 0.01).
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