Why the study?
Does left ventricular hypertrophy induced by aortic banding alter electrophysiologic properties and increase vulnerability to ventricular arrhythmias in intact cats?
Population
20 cats (15 underwent supraventricular aortic banding, 5 underwent sham procedure)
Comparison
Supraventricular aortic banding to induce… vs Sham procedure
Design
Preclinical
Follow-up
10 weeks
Authors
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LVH from pressure overload may heighten VF vulnerability in this model; leaves open translation to human arrhythmia risk.
Does left ventricular hypertrophy induced by aortic banding alter electrophysiologic properties and increase vulnerability to ventricular arrhythmias in intact cats?
In an intact cat model, left ventricular hypertrophy induced by chronic pressure overload increases vulnerability to ventricular fibrillation and inducibility of ventricular arrhythmias.
Shechter et al. (1989) studied this question.
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