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November 10, 2023The Journal of Cardiovascular Nursing

In patients with heart failure, quality of life was negatively correlated with left ventricular ejection fraction (r = -0.29, P = 0.02), and NYHA class III was associated with lower inspiratory pressures.

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Why the study?

Heart failure causes respiratory muscle alterations, dyspnea, fatigue, and exercise intolerance, worsening quality of life, but how respiratory muscle strength and quality of life correlate with clinical variables and functional classification needed analysis.

Population

60 patients with heart failure

Design

Cross-sectional study

Key result

In patients with heart failure, quality of life was negatively correlated with left ventricular ejection fraction (r = -0.29, P = 0.02), and NYHA class III was associated with lower inspiratory pressures.

Authors

INIsis Marinho de NoronhaLALarisse Xavier AlmeidaNANina Vitória de Souza Silva Andrade

Discussion

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Overview

Correlations of respiratory muscle strength with QoL and clinical variables in HF are hypothesis-generating; prospective studies needed before clinical relevance.

Study Design

Type

Cross-Sectional (n=60)

Structured PICO

P
Population
60 patients with heart failure (mean age 62.0 years, 33.3% female, mean LVEF 42.0%) assessed for respiratory muscle strength and quality of life.
O
Outcome
Respiratory muscle strength (maximum inspiratory and expiratory pressures) and quality of life (Minnesota Living with Heart Failure Questionnaire)patient reported

Main Result

Effect estimate: r = -0.29

p-value: p=0.02

In patients with heart failure, quality of life is moderately compromised and correlates with lower LVEF, longer disease duration, and NYHA class III, which is also associated with reduced inspiratory muscle strength.

Cite This Study

Noronha et al. (2023) conducted a cross-sectional in heart failure (n=60). Clinical variables (LVEF, NYHA class, disease duration) was evaluated on Quality of life (Minnesota Living with Heart Failure Questionnaire score) and respiratory muscle strength (r = -0.29, p=0.02). In patients with heart failure, quality of life was negatively correlated with left ventricular ejection fraction (r = -0.29, P = 0.02), and NYHA class III was associated with lower inspiratory pressures.

synapsesocial.com/papers/6a71c039f44fa9f079df76fdhttps://doi.org/10.1097/jcn.0000000000001062
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Heart failure-related myopathy. Clinical and pathophysiological insights1999 · 56 citations
  2. 2Breathing pattern, ventilatory drive and respiratory muscle strength in patients with chronic heart failure1994 · 104 citations
  3. 3Relationship of respiratory muscle strength, pulmonary function, and functional capacity with quality of life in patients with atrial fibrillation2017 · 9 citations
  4. 4Muscle Strength in Relation to Disease Severity in Patients with Congestive Heart Failure2007 · 44 citations
  5. 5Predictors of Functional Capacity in Patients With Heart Failure2010