Key result
Exercise training significantly increased brachial artery flow-mediated dilation by an absolute 1.7% (SMD 0.41) compared to control in patients with type 2 diabetes.
Why the study?
Does structured and supervised exercise improve endothelial function measured by flow-mediated dilation in adults with type 2 diabetes?
Population
306 adults with type 2 diabetes from 13 cohorts across 8 RCTs, average age 59 years, 45% female. Key…
Comparison
Structured and supervised exercise intervention… vs Control groups.
Design
Meta-analysis
Follow-up
mean 12 weeks (range 8 to 26 weeks)
Authors
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Supports exercise training to improve endothelial function in type 2 diabetes; extends prior evidence with pooled effect estimates.
Meta-Analysis (n=306)
Does structured and supervised exercise improve endothelial function measured by flow-mediated dilation in adults with type 2 diabetes?
Standardized Mean Difference: 0.41 (95% CI 0.21–0.62)
p-value: p=<0.001
Structured exercise training, particularly low-to-moderate intensity aerobic exercise, significantly improves vascular endothelial function in patients with type 2 diabetes.
Lee et al. (2018) conducted a meta-analysis in Type 2 diabetes (n=306). Exercise training vs. Control group was evaluated on Brachial artery flow-mediated dilation (FMD) (SMD 0.41, 95% CI 0.21-0.62, p=<0.001). Exercise training significantly increased brachial artery flow-mediated dilation by an absolute 1.7% (SMD 0.41) compared to control in patients with type 2 diabetes.
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