Why the study?
Does moricizine suppress sustained ventricular arrhythmias in patients refractory to class IA antiarrhythmic agents?
Population
21 patients with sustained ventricular arrhythmias refractory to treatment with class IA antiarrhythmic…
Design
Case_series
Follow-up
short-term
Authors
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Moricizine failed to suppress inducible VT in this series; leaves open its role and cautions against use in refractory patients with reduced LVEF.
Does moricizine suppress sustained ventricular arrhythmias in patients refractory to class IA antiarrhythmic agents?
Moricizine is ineffective and potentially proarrhythmic for suppressing sustained ventricular arrhythmias in patients with compromised left ventricular function who are refractory to class IA agents.
Powell et al. (1992) studied this question.
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