Why the study?
Does oral flecainide acetate improve suppression of PVCs compared to oral quinidine sulfate in patients with chronic premature ventricular complexes?
Population
280 patients with chronic premature ventricular complexes (PVCs)
Comparison
Oral flecainide acetate vs Oral quinidine sulfate
Design
RCT, double-blind
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Flecainide may be preferred over quinidine for chronic PVC suppression; confirms superior efficacy in this head-to-head RCT.
Does oral flecainide acetate improve suppression of PVCs compared to oral quinidine sulfate in patients with chronic premature ventricular complexes?
Oral flecainide is significantly more effective than quinidine for suppressing chronic premature ventricular complexes and complex ventricular arrhythmias.
A 1983 study studied this question.
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