August 17, 1979JAMA

Cardiogenic Shock and Disopyramide Phosphate

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Why the study?

Does oral disopyramide cause cardiogenic shock in a patient with severe heart failure?

Population

49-year-old man with rheumatic valvular heart disease, suspected associated congestive cardiomyopathy…

Design

Case_report

Authors

JSJames R. StorySpartanburg Regional Medical Center

Discussion

Member takes

Implication

Alerts to possible reversible shock with oral disopyramide in severe HF; single case leaves causality and frequency open.

Structured PICO

Does oral disopyramide cause cardiogenic shock in a patient with severe heart failure?

Population

49-year-old man with rheumatic valvular heart disease, suspected associated congestive cardiomyopathy, severe biventricular failure, massive pulmonary embolus, and frequent premature ventricular beats (n=1).

Intervention

Oral administration of disopyramide phosphate

Outcome

Development of reversible cardiogenic shocksafety

Oral disopyramide can precipitate reversible cardiogenic shock in patients with severe underlying heart failure.

Cite This Study

James R. Story (1979) studied this question.

synapsesocial.com/papers/6a71c2b075498292b70b2016 https://doi.org/10.1001/jama.1979.03300070050022

Topics

Heart failure HFrEF treatment

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