Population
Deendothelialized rat tail artery stimulated with phenylephrine
Design
Preclinical
Authors
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Forskolin relaxes rat arteries independently of specific K+ channels; leaves open translation to human hypertension therapy.
Forskolin-induced relaxation of intact rat tail artery occurs primarily through repolarization and reductions in the [Ca2+]i sensitivity of force, rather than through individual specific K+ channels.
Rembold et al. (1998) studied this question.
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