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August 1, 1995Cardiovascular Research

Cell geometry and contractile abnormalities of myocytes from failing human left ventricle

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Authors

FMFederica del MonteHeart Failure & Transplant POPeter O’GaraLung Institute PPP. A. Poole‐WilsonLung Institute

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Implication

Myocyte relaxation slowing supports cellular contribution to diastolic HF; leaves open translation to in vivo function or therapies.

Key Points

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Cite This Study

Monte et al. (1995) studied this question.

synapsesocial.com/papers/6a71c7f931a3df824329cfb2 https://doi.org/10.1016/s0008-6363(95)00040-2

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1From overload to failure: what happens inside the myocyte1998 · 8 citations
2Reduced Contraction and Altered Frequency Response of Isolated Ventricular Myocytes From Patients With Heart Failure1995 · 209 citations
3Alteration of contractile function and excitation-contraction coupling in dilated cardiomyopathy.1992 · 224 citations
4Regulation of Myofilament Contractile Function in Human Donor and Failing Hearts2020 · 23 citations
5Contractile responses of myocytes isolated from patients with cardiomyopathy1991 · 23 citations