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August 1, 1982CirculationOpen Access

Atrial repair of d-TGA in early infancy resulted in 0% mortality, with normal growth in 33 of 36 patients, sinus rhythm in 24 of 36 patients, and a normal cardiac index in all 28 catheterized patients at follow-up.

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Why the study?

What are the long-term clinical and hemodynamic outcomes of atrial repair of d-transposition of the great arteries performed in early infancy?

Population

52 patients younger than age 100 days with d-transposition of the great arteries and an intact…

Design

Cohort

Follow-up

mean 2.7 years (minimum 1.5 years)

Authors

LMLynn MahonyKTKevin TurleyPEP A Ebert

Discussion

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Overview

Supports favorable outcomes with early atrial repair of d-TGA; leaves open need for randomized comparisons with arterial switch.

Structured PICO

What are the long-term clinical and hemodynamic outcomes of atrial repair of d-transposition of the great arteries performed in early infancy?

P
Population
52 patients younger than age 100 days with d-transposition of the great arteries (d-TGA) and an intact interventricular septum or a small ventricular septal defect.
I
Intervention
Atrial repair of d-transposition of the great arteries (d-TGA)
O
Outcome
Long-term clinical and hemodynamic outcomes including mortality, growth, neurologic development, ECG findings, and catheterization results

Atrial repair of d-TGA in early infancy can be performed with zero mortality and a low incidence of late complications, maintaining good long-term hemodynamic outcomes.

Cite This Study

Mahony et al. (1982) studied this question.

synapsesocial.com/papers/6a71c8bb35aa2c282ce2ee12https://doi.org/10.1161/01.cir.66.2.253
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Anatomic correction of transposition of the great arteries associated with ventricular septal defect: midterm results in 50 patients.1984 · 47 citations
  2. 2Outcomes of 829 neonates with complete transposition of the great arteries 12–17 years after repair2003 · 187 citations
  3. 3Long-term outcome after atrial correction for transposition of the great arteries2018 · 36 citations
  4. 4Pregnancy after atrial repair for transposition of the great arteries1999 · 63 citations
  5. 5Midterm results after the arterial switch operation for transposition of the great arteries with intact ventricular septum: clinical, hemodynamic, echocardiographic, and electrophysiologic data.1988 · 142 citations