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November 10, 2018Heart

Long-term outcome after atrial correction for transposition of the great arteries

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Key result

Atrial correction for transposition of the great arteries was associated with 82% survival at 39.7 years postoperatively, alongside high morbidity including supraventricular tachycardia in 51%.

Population

76 adult patients with transposition of the great arteries (TGA) who underwent atrial correction, 59% male.

Design

Cohort

Follow-up

39.7 (IQR: 35.9-42.4) years postoperatively

Authors

LCLotte E. CouperusHVHubert W. VliegenTZTjitske E. Zandstra

Discussion

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Overview

Long-term survival after atrial TGA correction is tempered by high arrhythmia morbidity; extends prior cohorts yet leaves optimal management strategies open.

Study Design

Type

Cohort (n=76)

Structured PICO

P
Population
76 adult patients with transposition of the great arteries who underwent Mustard or Senning atrial correction, followed for a median of 39.7 years.
E
Exposure
Atrial correction according to Mustard or Senning technique
O
Outcome
Long-term survival and morbidity in three periods: early (<15 years), midterm (15-30 years) and late (>30 years postoperatively)hard clinical

While long-term survival nearly 40 years after atrial correction for TGA is high (82%), patients experience significant late morbidity including arrhythmias, heart failure, and depressed right ventricular function.

Cite This Study

Couperus et al. (2018) conducted a cohort in Transposition of the great arteries (TGA) (n=76). Atrial correction (Mustard or Senning) was evaluated on Adult survival. Atrial correction for transposition of the great arteries was associated with 82% survival at 39.7 years postoperatively, alongside high morbidity including supraventricular tachycardia in 51%.

synapsesocial.com/papers/6a205dae2b9ba068dd5ace58https://doi.org/10.1136/heartjnl-2018-313647
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Late outcome of Senning and Mustard procedures for correction of transposition of the great arteries2005 · 247 citations
  2. 2Long-Term Outcome of Mustard/Senning Correction for Transposition of the Great Arteries in Sweden and Denmark2015 · 149 citations
  3. 3Clinical factors affecting survival in patients with D-transposition of the great arteries after atrial switch repair: A meta-analysis2023 · 5 citations
  4. 4Interventions in leaks and obstructions of the interatrial baffle late after Mustard and Senning correction for transposition of the great arteries2005 · 43 citations
  5. 5Long-term results after atrial repair of transposition of the great arteries in early infancy.1982 · 63 citations