Key result
Ertapenem successfully treated a 70-year-old female patient with infective endocarditis caused by penicillin-resistant Abiotrophia defectiva.
Case Report (n=1)
Ertapenem may be a successful treatment option for infective endocarditis caused by penicillin-resistant Abiotrophia defectiva.
May support ertapenem for resistant A. defectiva IE; leaves open need for prospective trials.
The most frequently reported infections due to Abiotrophia defectiva worldwide are bacteraemia and endocarditis. It is estimated that A. defectiva causes approximately 5-6% of microbiologically proven endocarditis and plays a role in the etiology of culture negative endocarditis. In this article we reported a patient with infective endocarditis (IE) due to penicillin resistant A. defectiva, which caused vegetation in the mitral valve, embolism in the spleen and successfully treated with ertapenem. A 70-year-old female patient was admitted to the emergency service with fever and abdominal pain. The patient had a pronounced widespread abdominal tenderness in the left quadrant. The body temperature was 38.9 C, C-reactive protein (CRP) level was 12.7 mg/dl and white blood cell count was 13.3x10 3 mm 3 . The patient was hospitalized to investigate fever's reason. It was learned in the anamnesis that she used warfarin. Considering the pre-diagnosis of urinary tract infection, empirical treatment with ceftriaxone 2x1 g/day
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Duman et al. (2021) conducted a case report in Infective endocarditis due to Abiotrophia defectiva (n=1). Ertapenem was evaluated on Treatment success. Ertapenem successfully treated a 70-year-old female patient with infective endocarditis caused by penicillin-resistant Abiotrophia defectiva.
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