Key result
Treatment with amoxicillin and gentamicin followed by mitral valve replacement resulted in a favorable clinical outcome for a patient with Abiotrophia defectiva infective endocarditis.
Case Report (n=1)
No
Abiotrophia defectiva is a rare but severe cause of infective endocarditis that may require surgical intervention despite appropriate antibiotic therapy due to embolic complications.
Adds to sparse evidence on rare Abiotrophia endocarditis; hypothesis-generating and should not yet change practice.
Although relatively rare, infective endocarditis (IE) remains a severe disease that is associated with substantial morbidity and mortality especially in case of endocarditis caused by virulent microorganisms on valves in the left side. Appropriate antibiotic therapy is the most important component in the treatment of patients with IE. We report the case of a 67 year-old woman who was admitted for a native left sided IE. Transesophageal echocardiography (TEE) showed mitral valve vegetation with a moderate mitral regurgitation. Hemocultures were promptly positive but the identification of the germ needed an automated phenotypic system that isolated Abiotrophia defectiva, which is an exceptional entity. Despite the initiation of an appropriate antibiotic therapy, the patient experienced embolic episodes that prompted the decision for a surgical treatment.
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Kadri et al. (2015) conducted a case report in Infective endocarditis (n=1). Amoxicillin, gentamicin, and mitral valve replacement was evaluated on Clinical outcome. Treatment with amoxicillin and gentamicin followed by mitral valve replacement resulted in a favorable clinical outcome for a patient with Abiotrophia defectiva infective endocarditis.
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