Key result
A 41-year-old male with subacute endocarditis caused by Abiotrophia defectiva and complicated by septic emboli was successfully treated with a six-week course of vancomycin and gentamicin followed by mitral valve plasty.
Why the study?
Abiotrophia defectiva is a rare cause of endocarditis, and its subacute presentation may delay diagnosis.
Case Report (n=1)
New-onset valvular disease and stroke in an otherwise healthy young patient should prompt investigation for endocarditis, as rare agents like Abiotrophia defectiva can present subacutely and cause significant complications.
Illustrates feasible regimen for rare Abiotrophia defectiva endocarditis; extends sparse case reports but leaves optimal therapy open.
Abiotrophia defectiva is a rare agent of endocarditis and subacute presentation may delay the diagnosis. We present the case of a 41-year-old male who was admitted to the hospital for further investigation regarding a consumptive syndrome with microcytic anaemia. Past medical history included new-onset mitral insufficiency followed by an ischaemic stroke due to small vessel disease. Thoraco-abdominal computed tomography revealed a splenic infarction. In the presence of two ischaemic events associated with mitral valve disease of unknown aetiology, we considered the possibility of subacute endocarditis. Blood cultures were positive for Abiotrophia defectiva, and transoesophageal echocardiography confirmed the diagnosis. As a subacute presentation of endocarditis, the paucity of symptoms caused a five-month delay in diagnosis. New-onset valvular disease and a stroke in an otherwise healthy young patient should always prompt proper investigation. This case highlights several complications caused by septic emboli of undiagnosed and untreated endocarditis.
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Faria et al. (2021) conducted a case report in Subacute endocarditis caused by Abiotrophia defectiva (n=1). Vancomycin and gentamicin followed by mitral valve plasty was evaluated on Patient recovery. A 41-year-old male with subacute endocarditis caused by Abiotrophia defectiva and complicated by septic emboli was successfully treated with a six-week course of vancomycin and gentamicin followed by mitral valve plasty.
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