Key result
Combined surgery and antimicrobial therapy successfully resolves relapsed Abiotrophia defectiva infective endocarditis.
Why the study?
Infective endocarditis caused by Abiotrophia defectiva can present with atypical clinical features and relapse despite initial antibiotic therapy.
Case Report (n=1)
Abiotrophia defectiva is an uncommon but important cause of infective endocarditis that can present with atypical symptoms and has a risk of relapse requiring surgical intervention.
May warrant surgery after relapse in Abiotrophia endocarditis; leaves open optimal regimens for this rare pathogen.
A case of infective endocarditis caused by an uncommon agent Abiotrophia defectiva with atypical manifestations is presented. A 42-year-old woman previously had rheumatic heart disease, presented with the symptoms of fever and chills that resolved within 3 days under antibiotherapy. She was diagnosed with endocarditis due to A. defectiva. Despite culture-directed antibiotics being administered in the first admission, her symptoms and also blood culture growth relapsed 3 weeks later. She was successfully treated with antimicrobial therapy and surgical intervention including aorta and mitral valve replacement. This case demonstrates that A. defectiva should be considered as a causative organism of endocarditis particularly in the presence of atypical symptoms and should be followed up carefully in terms of relapses and complications.
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Bozkurt et al. (2016) conducted a case report in Infective endocarditis (n=1). Antimicrobial therapy and surgical intervention (aorta and mitral valve replacement) was evaluated. A 42-year-old woman with infective endocarditis caused by Abiotrophia defectiva was successfully treated with antimicrobial therapy and surgical intervention after an initial relapse.
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