Key result
A low score (<6) on the Korean version of the 8-item Morisky Medication Adherence Scale was significantly associated with a 5-fold increased odds of poor blood pressure control (adjusted OR 5.08).
Why the study?
Does the Korean version of the MMAS-8 reliably and validly measure medication adherence and associate with blood pressure control in adults with hypertension?
Cross-Sectional (n=373)
Yes
Does the Korean version of the MMAS-8 reliably and validly measure medication adherence and associate with blood pressure control in adults with hypertension?
Odds Ratio: 5.08 (95% CI 2.56–10.08)
Absolute Event Rate: 29.5% vs 8%
p-value: p=<0.001
The Korean version of the MMAS-8 is a reliable and valid tool for assessing medication adherence in hypertensive patients, with low scores strongly predicting poor blood pressure control.
Supports Korean MMAS-8 screening in hypertension; leaves open whether routine use improves adherence or BP outcomes.
BACKGROUND: We examined the psychometric properties of the Korean version of the 8-item Morisky Medication Adherence Scale (MMAS-8) among adults with hypertension. METHODS: A total of 373 adults with hypertension were given face-to-face interviews in 2 cardiology clinics at 2 large teaching hospitals in Seoul, South Korea. Blood pressure was measured twice, and medical records were reviewed. About one-third of the participants (n = 109) were randomly selected for a 2-week test-retest evaluation of reliability via telephone interview. RESULTS: Internal consistency reliability was moderate (Cronbach α = 0.56), and test-retest reliability was excellent (intraclass correlation = 0.91; P < 0.001), although a ceiling effect was detected. The correlation of MMAS-8 scores with scores for the original 4-item scale indicated that convergent validity was good (r = 0.92; P < 0.01). A low MMAS-8 score was significantly associated with poor blood pressure control (χ(2) = 29.86; P < 0.001; adjusted odds ratio = 5.08; 95% CI, 2.56-10.08). Using a cut-off point of 6, sensitivity and specificity were 64.3% and 72.9%, respectively. Exploratory factor analysis identified 3 dimensions of the scale, with poor fit for the 1-dimensional construct using confirmatory factory analysis. CONCLUSIONS: The MMAS-8 had satisfactory reliability and validity and thus might be suitable for assessment and counseling regarding medication adherence among adults with hypertension in a busy clinical setting in Korea.
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Kim et al. (2014) conducted a cross-sectional in Hypertension (n=373). Low medication adherence (MMAS-8 score <6) vs. Moderate to high medication adherence (MMAS-8 score ≥6) was evaluated on Poor blood pressure control (systolic BP ≥140 mm Hg or diastolic BP ≥90 mm Hg) (adjusted OR 5.08, 95% CI 2.56-10.08, p=<0.001). A low score (<6) on the Korean version of the 8-item Morisky Medication Adherence Scale was significantly associated with a 5-fold increased odds of poor blood pressure control (adjusted OR 5.08).
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