Key result
Severe/very severe hypertriglyceridemia in acute pancreatitis was independently associated with persistent organ failure (OR 4.9; P=0.009) compared to normal triglyceride levels.
Why the study?
Does hypertriglyceridemia increase the risk of persistent organ failure in patients with acute pancreatitis?
Population
201 prospectively enrolled patients with acute pancreatitis who had serum triglycerides measured within 72…
Comparison
Hypertriglyceridemia vs Normal triglyceride levels
Design
Cohort
Authors
Loading...
May support triglyceride assessment in acute pancreatitis; leaves open whether lowering levels prevents organ failure.
Cohort (n=201)
Does hypertriglyceridemia increase the risk of persistent organ failure in patients with acute pancreatitis?
Odds Ratio: 4.9
Absolute Event Rate: 48% vs 17%
p-value: p=0.009
Elevated serum triglycerides in acute pancreatitis are independently and proportionally associated with an increased risk of persistent organ failure.
Nawaz et al. (2015) conducted a cohort in Acute pancreatitis (n=201). Elevated serum triglycerides vs. Normal serum triglycerides was evaluated on Persistent organ failure (OR 4.9, p=0.009). Severe/very severe hypertriglyceridemia in acute pancreatitis was independently associated with persistent organ failure (OR 4.9; P=0.009) compared to normal triglyceride levels.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: