Key result
A 14-year-old boy with T-cell lymphoblastic lymphoma presented with cardiac tamponade masking restrictive cardiomyopathy, which was revealed after pericardiocentesis.
Why the study?
Restrictive cardiomyopathy from tumor infiltration is rare in T-cell lymphoma, and heart failure symptoms in pericardial effusion may mask underlying myocardial disease until pericardiocentesis is performed.
Case Report (n=1)
T-cell lymphoblastic lymphoma can present atypically with cardiac tamponade masking restrictive cardiomyopathy, highlighting the need for careful echocardiographic reassessment after pericardiocentesis.
May prompt post-pericardiocentesis reevaluation in pediatric T-cell lymphoma with effusion; leaves open true incidence of infiltrative RCM.
Cardiac involvement in T-cell lymphoma is not uncommon. Pericardial effusion is the most common manifestation of cardiac involvement with restrictive cardiomyopathy (RCM) due to tumor infiltration being extremely rare. The presence of paroxysmal nocturnal dyspnea and orthopnea in a patient presenting with pericardial effusion could be related to tamponade or underlying myocardial disease. Hence, reevaluation after pericardiocentesis is warranted. We describe a 14-year-old boy with advanced T-cell lymphoma presenting with cardiac tamponade. Repeat echocardiography after pericardiocentesis revealed mediastinal mass infiltrating cardiac chambers and great vessels along with features of RCM secondary to tumor infiltration.
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Gawalkar et al. (2022) conducted a case report in T-cell lymphoblastic lymphoma with cardiac tamponade and restrictive cardiomyopathy (n=1). Pericardiocentesis and chemotherapy was evaluated on Clinical outcome. A 14-year-old boy with T-cell lymphoblastic lymphoma presented with cardiac tamponade masking restrictive cardiomyopathy, which was revealed after pericardiocentesis.
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