Why the study?
Does nifedipine GITS reduce mortality, morbidity, and atherosclerosis progression in hypertensive patients compared to standard diuretic treatment?
Population
Hypertensive patients, including elderly patients with systolic hypertension, black patients, and those with…
Comparison
Nifedipine GITS once-daily vs Standard diuretic treatment
Design
Review
Authors
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Nifedipine GITS may be considered comparable to diuretics for CV outcomes in high-risk hypertension; leaves open prospective confirmation of atherosclerosis slowing.
Does nifedipine GITS reduce mortality, morbidity, and atherosclerosis progression in hypertensive patients compared to standard diuretic treatment?
Nifedipine GITS is an effective, once-daily calcium channel blocker that provides comparable cardiovascular protection to standard diuretics in hypertensive patients, while also slowing atherosclerosis progression.
Simon et al. (2003) studied this question.
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