Why the study?
Does sodium restriction alter renal vascular sensitivity to angiotensin and norepinephrine in normal humans?
Does sodium restriction alter renal vascular sensitivity to angiotensin and norepinephrine in normal humans?
Sodium restriction decreases renal vascular sensitivity to angiotensin while increasing sensitivity to norepinephrine in normal humans, suggesting circulating angiotensin may mediate renal vascular tone.
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Sodium restriction may differentially modulate renal vascular reactivity in normals; leaves open relevance to hypertension or heart failure.
Hollenberg et al. (1972) studied this question.
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