Key result
Urolithiasis was associated with impaired cardiac diastolic function, demonstrated by a lower E/A ratio and a higher frequency of diastolic dysfunction compared to controls.
Why the study?
Is urolithiasis associated with impaired cardiac diastolic function in patients without known cardiovascular disease?
Cross-Sectional (n=117)
No
Is urolithiasis associated with impaired cardiac diastolic function in patients without known cardiovascular disease?
Answers are grounded in this paper and cite their sources.
Urolithiasis is associated with impaired cardiac diastolic function independent of traditional cardiovascular risk factors.
Relationships between urolithiasis and cardiovascular disorders were evaluated in several studies. In this study, we aimed to investigate whether urolithiasis causes a decline in cardiac diastolic functions. Materials and methods: Seventy-seven consecutive patients and 40 age- and sex-matched controls were included in this study. Transthoracic echocardiography was performed for all patients. Results: There were 77 patients (mean age: 45 ± 14 years, 64% male) in the stone-formers group and 40 patients (mean age: 43 ± 12 years, 63% male) in the control group. Peak E wave velocity (0.67 ± 0.21 to 0.85 ± 0.18, P = 0.001) and E/A ratio (0.97 ± 0.21 to 1.37 ± 0.27, P = 0.001) were significantly lower in stone formers than in control patients. In addition, peak A wave velocity (0.74 ± 0.15 to 0.69 ± 0.14) was significantly higher in stone formers than control patients (P = 0.01). Diastolic dysfunction was more frequent in stone formers than control patients (P = 0.015). Conclusion: This study shows that there is a link between urolithiasis and cardiac diastolic dysfunction. Urolithiasis should therefore be recognized in evaluation of patients with diastolic dysfunction.
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İnci et al. (2013) conducted a cross-sectional in Urolithiasis (n=117). Urolithiasis vs. Age- and sex-matched controls without urinary tract stones was evaluated on E/A ratio (p=0.001). Urolithiasis was associated with impaired cardiac diastolic function, demonstrated by a lower E/A ratio and a higher frequency of diastolic dysfunction compared to controls.
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