Why the study?
Does diltiazem reduce the cardiovascular response to laryngoscopy and tracheal intubation in patients undergoing elective surgery?
Population
30 patients undergoing elective surgery (3 groups of 10 patients each)
Comparison
Diltiazem 0.2 or 0.3 mg/kg bolus injection 60… vs Saline
Follow-up
Immediate (during intubation)
Authors
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May blunt intubation pressor response; leaves open whether it improves outcomes or warrants routine use.
Does diltiazem reduce the cardiovascular response to laryngoscopy and tracheal intubation in patients undergoing elective surgery?
A bolus injection of diltiazem prior to laryngoscopy is a simple and effective method to attenuate the hypertensive response associated with tracheal intubation.
Mikawa et al. (1990) studied this question.
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