Population
Isolated rat cardiomyocytes and isolated hearts
Comparison
Treatment with Ca2+ movement modifiers in the… vs Control conditions without specific blockers
Design
Preclinical
Authors
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May implicate NCX in adrenergic calcium handling; leaves open relevance to intact models or clinical translation.
The sarcolemmal Na+/Ca2+ exchanger, in addition to L-type Ca2+ channels, plays a significant role in mediating catecholamine-induced increases in intracellular calcium in cardiomyocytes.
Saini et al. (2005) studied this question.
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